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Clove Bud (Eugenia caryophyllata), Thyme ct thymol (Thymus vulgaris), Wild Orange (Citrus sinensis), Frankincense (Boswelia frereana/carterii)
Children? Skin irritation risk; use with caution on children under 2 years of age.
Pregnancy/Breastfeeding? Use with caution. Thyme ct thymol should be avoided orally before major surgery. Clove may inhibit blood clotting - use with discretion.
Medication/Health Condition? Contraindicated orally: Anticoagulant, Diabetes medication, Diet drug (Ephedrine), Pethidine; Childbirth, Liver and Kidney disease (all routes), Major Surgery (one week before and after), Peptic Ulcer, Hemophilia
Therapeutic Uses
Endurance essential oil blend may support, aid, ease, soothe, reduce, calm, relax, promote and/or maintain healthy function of the following:
Immune system
Joint, minor aches and pain
Muscle, minor aches and pain
Application Suggestions (See Essential Oil Usage for more information and a dilution chart.)
Topical: Dilute with a carrier oilunscented lotion or unscented cream and apply on area of concern or as desired. Consider using a roll-on applicator for ease of application of prediluted oil. Use topically with caution if one is hypersensitive, has diseased or damaged skin and on children under 2 years of age. The maximum topical use is 2.5%.
Phototoxic Caution: Orange oil is phototoxic unless appropriately diluted. Avoid exposure to direct sunlight or UV light if applying to exposed skin.

Inhalation: Diffuse or use a personal Nasal Inhaler

Internal: Endurance is suitable for internal use within safe parameters if such use is deemed appropriate. We feel that internal use is rarely *needed* and should only be used with respect for how concentrated the oils are. HEO does not advocate internal use of essential oils without appropriate knowledge and understanding of how to administer, for what purpose, how much, which essential oils, safety concerns and so on. In our experience, essential oils are generally more effective used topically with proper dilution or inhaled. Kurt Schnaubelt Ph.D. notes that "French aromatherapy literature contains many references to using oils orally." He goes on to note that "generally 1 drop is always enough when ingesting essential oils." A potential toxicity hazard could occur when untrained people use essential oils orally and ingest too much. Keep in mind that while medical doctors or health care practitioners may prescribe essential oils for internal use, they are trained and experienced in the safe application of essential oils. It is not a matter of using "French" or "British" methods, it's a matter of experience and appropriate application.
Click here for information about internal usage.

Phototoxic: Orange oil is phototoxic unless appropriately diluted. Avoid exposure to direct sunlight or UV light if applying to exposed skin.

Drug interaction Caution (oral): anticoagulant medication, major surgery, peptic ulcer, hemophilia and other bleeding disorders (Tisserand p. 255).
Tisserand notes that "since eugenol significantly inhibits human MAO-A (Tao et al 2005), oral doses of eugenol-rich essential oils may interact with pethidine, indirect sympathomimetics, MAOIs or SSRIs." Caution is advised when Clove essential oil is ingested in conjunction with certain foods if taking MAO inhibiting antidepressants. Those containing tyramine, which include cheese, may precipitate a hypertensive crisis (Blackwell ? Mabbitt 1965), while tryptophan-containing foods may lead to elevated serotonin levels.

Dermal Caution: For those who are hypersensitive, have diseased or damaged skin and children under 2 years of age.

Repeated use can result in contact sensitization. Skin test for sensitivity.

From Essential Oil Safety by Robert Tisserand, page 254-256: Clove caution: "Hypersensitive, diseased or damaged skin, children under 2 years of age." "There are three reports of non-fatal oral poisoning from clove oil, all in children. In 1991 a 7-month-old child was given one teaspoon of clove oil. Supportive care and gastric lavage were sufficient for total recovery following the resultant severe acidosis, CNS depression and urinary abnormalities (the presence of ketones in the urine). The second case involves a near fatal poisoning of the acetaminophen (paracetamol) type after ingestion of 5-10 ml of clove oil by a 2-year-old boy. Acidosis, deteriorating liver function, deep coma, generalized seizure and unrecordably low blood glucose were all noted. Heparin (an anticoagulant) was given due to the possible development of disseminated intravascular coagulation. The child was fully conscious by day six and eventually made a full recovery. In the final case, a 15-month-old boy developed fulminant hepatic failure after ingesting 10ml clove oil. . . . a 32-year-old woman, who self-injected an unknown quantity of clove oil intravenously, experienced acute respiratory distress due to pulmonary edema which had developed over one hour."

Avoid contact with the eyes and other sensitive areas. Essential oils are both lipophilic and hydrophobic. Lipophilic means they are attracted to fat— like the membranes of your eyes and skin. They are also hydrophobic, meaning they do not like water. Applying a carrier oil will create another fat for the essential oil to be attracted to other than the membranes of the eyes or skin. Tisserand suggests: "With essential oils, fatty oil has been suggested as an appropriate first aid treatment, though the advantage of saline [eyewash] is that the eyes can be continually flushed, and this is less easy with fatty oil.” We are not aware of a case where essential oil in the eyes caused permanent injury or long-term discomfort, but if you feel concerned, please call your health care provider. 
Tisserand, Robert; Young, Rodney, Essential Oil Safety: A Guide for Health Care Professionals, Elsevier Health Sciences UK, 2013, page 64, 254-256.