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Grapefruit

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(Citrus paradisi)
Traditionally used to support healthy lymph, liver, digestion and fluid levels, soothe minor skin issues, ease mental fatigue and jet lag.

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Grapefruit
Citrus paradisi
Plant Origin: USA
Method: Cold pressed from rind
Cultivation: Unsprayed (grown organically but not certified)
Chemical Family: Monoterpenes
Aroma: Citrus, bittersweet, fresh, fruity
Note (Evaporation Rate): Top Note
Shelf Life: approximately 6 months once opened - keep in a cool place (refrigerate if possible)
Key Constituents Lot#113
limonene 92.56%
a-pinene 0.62%
mycrene 2.04%
nootkatone 0.07% (responsible for the aroma)
Safety Information
Children: 
Suitable

Pregnancy/Breastfeeding: Suitable

Medication/Health Issue: There are no known contraindications. To avoid skin sensitization risk, do not use old and oxidized oils.

Phototoxic Caution: Tisserand notes that Grapefruit is a slightly photosensitizing oil but is considered safe at 4% dilution, which is about 36 drops per ounce of carrier.
Therapeutic Uses Grapefruit expressed oil may support, aid, ease, soothe, reduce, calm, relax, promote and/or maintain healthy function of the following:
Acne
Antibacterial  
Antioxidant  
Antiviral (d-limonene activates white blood cells) 
Anxiety (inhalation has anxiolytic action) 
Appetite, 'Dieter’s Friend' (inhaling may reduce sweet cravings) 
Astringent
Cellulite 
Detoxifying 
Digestion 
Disinfecting 
Diuretic  
Drug withdrawal 
Eating disorders 
Fatigue 
Fatty tumor 
Fluid retention 
Headaches/migraines 
Hepatitis
Hot Flashes
Immune support 
Inflammation 
Irritable bowel syndrome 
Jet lag 
Kidneys 
Lipoma 
Liver support (hepatoprotective action) 
Lymphatic 
Muscular weakness/fatigue 
Night Sweats
Pain 
PMS 
Skin, aging (especially oily skin) 
Skin penetration enhancer 
Stress 
Uplifting

Hopewell Essential Oil Blends containing Grapefruit
Citrus Blessing
Citrus Quench
Dr. Hull's Lymph Venous
Dr. Hull's Mental Stimulation
Escape
FibroSoothe
Liver / Gallbladder
Lymphatic Cleanse
Tropical Trio

Blends well with:
Citrus oils
Cardamom
Coriander
Cypress
Juniperberry
Lavender
Neroli
Petitgrain
Pine
Geranium
Rosemary
Blend with Frankincense and Lemongrass for immune support when overworked and exhausted.  

Research
Purchon notes that "a study found that grapefruit essential oil shows promise against hospital-acquired infections and antibiotic-resistant bacteria. This suggests that it is an effective topical antiseptic treatment option, even for antibiotic-resistant strains such as MRSA and antimycotic-resistant Candida species." (Purchon does not site the specific study.)

Grapefruit essential oil and d-Limonene can increase the synthesis rate of glutathione S-transferase in the liver. This is an important enzyme in detoxification pathways (Tisserand and Young 2014). Bodake et al. (2002) and Ozbek et al. (2003) noted that d-limonene had hepatoprotective action.
 
Research shows that inhalation of d-limonene has anxiolytic actions (anxiety reducing) (Lima et al. 2012). 

In Regard to using Statin Drugs, Is Grapefruit Essential Oil the same as Eating Grapefruit?
Research shows that dihydroxybergamottin found in grapefruit juice blocks a special enzyme in the wall of the intestine that prevents many drugs from being absorbed into the body making it easier for these medications to pass from the gut into the body, raising the blood levels of these drugs, which can create dangerous, toxic effects. So the question is asked, "What about the essential oil of Grapefruit?" You cannot equate the use of a whole herb or fruit with the use of an essential oil. Essential oils are only a small fraction of the whole plant. They are only the volatile aromatic molecules, which is typically less than 1% of the plant. Grapefruit juice is from the meat of the fruit, while essential oils are expressed or distilled from the rind. They are not one and the same. 

Robert Tisserand wrote: A pharmacist asked about whether grapefruit oil would interact with statins, cholesterol-lowering drugs, as grapefruit juice does. My answer was no, since the main compound in grapefruit juice responsible for drug interactions is not found in the essential oil.

Application Suggestions (See Essential Oil Usage for more information and a Dilution Chart.)
Topical: Dilute with a carrier oilunscented lotion or unscented cream and apply on area of concern or as desired. Consider using a roll-on applicator for ease of application of prediluted oil. Grapefruit was not irritating when tested at 10% or 100% on two panels of volunteers. It was not sensitizing when tested at 10% on 25 volunteers.

Since Grapefruit does not have a limiting dilution parameter, we suggest that adults follow the General Guidelines found on the Dilution Chart, which is:
2-3% for daily application
Up to 25% for short-term use 
 
Children: For infants and children, please follow the Dilution Chart on the Babies and Children page. 

Phototoxic Caution: Tisserand notes that Grapefruit is a slightly photosensitizing oil but is considered safe at 4% dilution, which is about 36 drops per ounce of carrier.

Inhalation: Diffuse or use a personal Nasal Inhaler

Internal: Grapefruit is suitable for internal use within safe parameters if such use is deemed appropriate. We feel that internal use is rarely *needed* and should only be used with respect for how concentrated the oils are. HEO does not advocate internal use of essential oils without appropriate knowledge and understanding of how to administer, for what purpose, how much, which essential oils, safety concerns and so on. In our experience, essential oils are generally more effective used topically with proper dilution or inhaled. Kurt Schnaubelt Ph.D. notes that "French aromatherapy literature contains many references to using oils internally." He goes on to note that "generally 1 drop is always enough when ingesting essential oils." A potential toxicity hazard could occur when untrained people use essential oils orally and ingest too much. Keep in mind that while medical doctors or health care practitioners may prescribe essential oils for internal use, they are trained and experienced in the safe application of essential oils. It is not a matter of using "French aromatherapy" or "British" methods, it's a matter of experience and appropriate application. Click here for information about internal usage.

Testimonies
The following anecdotal testimonies have not been reviewed by the FDA.
The products mentioned are not intended to diagnose, prevent, treat or cure disease.
Information shared on the HEO website is not intended to be a substitute for medical advice given by your trusted health care provider.
We believe that essential oils are provided by the Lord to support our health and well-being.
The Lord is our wisdom, protector and healer.
(Genesis 1:29-30, Ezekiel 47:12) 
1. My new favorite water enhancer...GRAPEFRUIT! It's subtle and sweet . . . even better than Lemon. - Susan

2. An aromatherapist wrote: "Grapefruit digests fat deposits in the liver. It works with Frankincense on fatty tumors. However, if using it, triple your water intake or the fatty tumors will move to a new location. It also works as an air purifier for air bacteria."

3. I know from my own personal experience with lipomas (fatty tumors), it is necessary to use the oil for a very long time and be consistent with it. Grapefruit is said to dissolve adipose, or fat tissue. I know I have watched the lipomas in my arm shrink dramatically in size as I have been persistent with using Grapefruit EO. 
Cinda Reeves, LMT

4. Grapefruit oil has been helpful along with Geranium during PMS to help curb the cravings, helps with bloating and digestion and helps to fight off fatigue that comes during that time. Sometimes I take a drop in water, and sometimes I will put a drop on my wrists. Thank you for your ministry of providing God's healing oils. I have been sharing my oil stories with others often and have directed many people your way to reap the same benefits. God bless!! - Jenn

5. Grapefruit makes a very uplifting room freshener and linen spray. I make the spray using Everclear. When I go out, my friends love my 'perfume'! - Callie
[HEO's Comment: Callie didn't mention her exact recipe, but this may be a good starting point:
Room/Linen Spray
Everclear is the best solvent for the essential oil. If you use Vodka, it will separate and will need to be shaken with each use.
1oz spray bottle
120 drops essential oil of choice
Everclear to the 'shoulder' of the bottle
Safety
Phototoxic Caution: Tisserand notes that Graperfruit is a slightly photosensitizing oil but is considered safe at 36 drops per ounce of carrier. Foster, on the other hand writes that Grapefruit is not phototoxic to humans (Battaglia, page 211).

Avoid contact with the eyes and other sensitive areas. Essential oils are both lipophilic and hydrophobic. Lipophilic means they are attracted to fat— like the membranes of your eyes and skin. They are also hydrophobic, meaning they do not like water. Applying a carrier oil will create another fat for the essential oil to be attracted to other than the membranes of the eyes or skin. Tisserand suggests: "With essential oils, fatty oil has been suggested as an appropriate first aid treatment, though the advantage of saline [eyewash] is that the eyes can be continually flushed, and this is less easy with fatty oil.” We are not aware of a case where essential oil in the eyes caused permanent injury or long-term discomfort, but if you feel concerned, please call your health care provider.  
Reference
Battaglia, Salvatore, The Complete Guide to Aromatherapy, 2002, pages 210-211.
Purchon, Nerys; Cantele, Lora, Complete Aromatheapy and Essential Oils Handbook for Everyday Wellness, page 63.
Tisserand, Robert; Young, Rodney (2013-12-02). Essential Oil Safety: A Guide for Health Care Professionals, Elsevier Health Sciences UK 2nd Edition 2014, page 297-298.
Wildwood, Chrissie, Bloomsbury Encyclopedia of Aromatherapy, 1996, page 267.
Worwood, Valerie Ann, The Complete Book of Essential Oils and Aromatherapy, New World Library, 2016, page 592-593.
 
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May the Lord guide you continually, preserving your health and watering your life when you are dry. May you be like a well-watered garden, like an ever-flowing spring full of hope for your future in His care.
From Isaiah 58:11 & Jeremiah 29:11