(Copaifera langsdorfii) Traditionally used to support healthy skin, breathing, digestion and bladder function.
Research Antibacterial Activity of Copaiba Oil Gel on Dental Biofilm
Using doses of 100-200 mg/kg (3-7 drops) either orally, or through sub-cutaneous or intra-peritoneal injections, the researchers found that the mice tested (5 per test group) demonstrated behaviors as if beta-caryophyllene had anti-panic/anti-anxiety effects. beta- caryophyllene did not affect either serotonin or benzodiazepine pathways (the usual pathways for modulating anxiety), so its effects may be due primarily to interaction with CB2 receptors in the brain (Galdino et al 2012). Copaiba oil has a relatively high level of beta-caryophyllene, which has also been shown to have anti-inflammatory and pain-relieving properties.
For psoriasis, Copaiba oleoresin was given orally 1-7 drops per day, escalating dose over 1 week. For a 36-year-old female with an 8 year history of psoriasis on her right arm that was resistant to other treatment, the condition completely resolved after 3 months and had not returned 12 months later. For a 45-year-old man with an 8 year history of psoriasis on both legs that was resistant to other treatment, the condition completely resolved after 3 months and had not returned 12 months later. For topical treatment: 94% Shea butter, 5% Copaiba oleoresin and 0.1% Tea Tree was applied twice daily on both elbows of a 36-year-old man with psoriasis lesions. He showed improvement after 6 weeks. (Gelmini et al 2013)
Copaiba was cytotoxic to B16F10 (mouse) melanoma cells in vitro, and oral administration significantly reduced lung tumors (which had metastasized from injected B16F10 cells) in mice (Lima et al 2003). Research suggests that beta caryophyllene has these properties: analgesic (pain relieving), anti-inflammatory, antibacterial, antibiofilm, antinociceptive (relieves nerve pain), antispasmodic, antitumoral, antiviral, calming, immune supportive, local anaesthesia, neuroprotective, protection against atherosclerosis and cardiovascular disease